Primary adenocarcinoma of bladder

• Published in: Urology (Ridgewood, N.J.) Vol. 38; no. 3; pp. 223 - 226
• Main Authors: Wilson, Timothy G., Pritchett, T. Rand, Lieskovsky, Gary, Warner, Nancy E., Skinner, Donald G.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.09.1991; Elsevier Science
• Subjects: Actuarial Analysis; Adenocarcinoma - mortality; Adenocarcinoma - surgery; Biological and medical sciences; Cystectomy; Female; Follow-Up Studies; Humans; Lymph Node Excision; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Prognosis; Tumors of the urinary system; Urinary Bladder Neoplasms - mortality; Urinary Bladder Neoplasms - surgery; Urinary Diversion; Urinary tract. Prostate gland; Adenocarcinoma; Human; Urinary system disease; Treatment; Urinary bladder; Tumor; Urinary tract disease; Malignant tumor
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/S0090-4295(91)80349-C

Between April 1983 and December 1987, we have treated and followed 16 patients at the University of Southern California for adenocarcinoma of the bladder. In 10 patients, the cancer originated from a nonurachal source; all underwent radical cystectomy, bilateral pelvic lymph node dissection, and urinary diversion. The other 6 patients had an apparent urachal origin of their cancer. Half of these patients were treated with radical cystectomy and urinary diversion and half were treated initially with segmental cystectomy. Presenting characteristics (age, sex ratio, and symptoms) were similar for both groups. Three-year adjusted actuarial tumor free survival rates for the two groups were 48 percent and 31 percent, respectively. We advocate an aggressive approach of radical cystectomy, bilateral pelvic lymph node dissection, and urinary diversion for all invasive adenocarcinoma of the bladder, regardless of location.