Trends in stroke mortality in La Rioja (Spain) from 1999 to 2022

• Published in: Journal of stroke and cerebrovascular diseases Vol. 32; no. 11; p. 107334
• Main Authors: Ramalle-Gómara, Enrique, Palacios-Castaño, María-Isabel, Martínez-Ochoa, Eva, Quiñones-Rubio, Carmen, Julian-Villaverde, Francisco-José, Marzo-Sola, María-Eugenia
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.11.2023
• Subjects: Hemorrhagic stroke; Ischemic stroke; Joinpoint regression analysis; Mortality; Stroke; Trends; Stroke; Ischemic stroke; Trends; Hemorrhagic stroke; Mortality; Joinpoint regression analysis
• ISSN: 1052-3057; 1532-8511
• DOI: 10.1016/j.jstrokecerebrovasdis.2023.107334

Stroke mortality has declined in recent decades, but there appears to be a slowdown in the decline in recent years. We analyze the trends in stroke mortality in La Rioja (Spain) for the period 1999–2022. We evaluated stroke mortality using statistical data from the mortality registry of La Rioja (Spain). We adjusted the rates by age and sex and analyzed both overall strokes and subtypes: hemorrhagic and ischemic. To analyze the trend in mortality rates we constructed joinpoint regression models, with associated annual percentage change (APC) Age-standardized stroke mortality declined between 1999 and 2022: females from 98.0 to 29.2 per 100 000; males, from 131.6 to 44.8 per 100 000. We found a decrease in overall stroke mortality in all age groups, except those under 65 years old. Ischemic stroke mortality showed declines in the first decade (APC: 7.3%, CI95%: 4.1–19.1%) and increases in the second decade (APC: 1.6%, CI95%: -1.6–11.7%) among men. In women, the rates declined between 2018 and 2022(APC: -6.6%, CI95%: -5.1–30.6%) after an increase between 2015 and 2017 (APC: 23.5%, CI95%: -20.2–38.3%). For hemorrhagic stroke, we found a consistent rate of decline throughout the entire time period in men (APC: 2.4%, CI95%: 0.9 a 4.0%). In women, rates increased during the period 1999-2009(APC: 1.9%, CI95%: -2.1–22.8%) and decreased 2010-2022 (APC: 6.5%, CI95%: 4.0–25.6%). Stroke mortality rates have decreased, more so for haemorrhagic than ischaemic strokes.