Synchronous Appearance of Adenocarcinoma and Gastrointestinal Stromal Tumour (GIST) of the Stomach: A Case Report

• Published in: Journal of clinical and diagnostic research Vol. 10; no. 2; pp. ED16 - ED18
• Main Authors: Telugu, Ramesh Babu, Pushparaj, Magesh, Masih, Dipti, Pulimood, Anna
• Format: Journal Article
• Language: English
• Published: India JCDR Research and Publications (P) Limited 01.02.2016; JCDR Research and Publications Private Limited
• Subjects: carcinoma; gastric; mesenchymal neoplasm; Pathology Section; Gastric; Carcinoma; Mesenchymal neoplasm
• ISSN: 2249-782X; 0973-709X
• DOI: 10.7860/JCDR/2016/17636.7289

Adenocarcinoma is the most common histological type of gastric tumour, accounting for approximately 95% of all gastric carcinomas. Gastrointestinal stromal tumours (GISTs) are rare mesenchymal neoplasms of the digestive tract. Synchronous adenocarcinoma and gastrointestinal stromal tumour (GIST) occurring in the stomach is rare and very few cases have been reported in literature. Synchronous tumours in the stomach are rarely diagnosed preoperatively. A 63-year-old gentleman was diagnosed with a gastric adenocarcinoma on endoscopic biopsy and underwent surgery. Postoperative histopathologic examination revealed 2 synchronous tumours with both adenocarcinoma and GIST. The adenocarcinoma was determined to be the aggressive tumour based on histologic features. GIST was categorized as a very low risk of malignancy, based on its size and mitosis. The patient underwent chemotherapy for adenocarcinoma. He is under follow up and is currently disease free. Careful histopathologic evaluation is required to detect co-existing rare synchronous tumours. Presence of the second tumour may require additional procedures or protocols.