Response of turkey poults to soybean lectin levels typically encountered in commercial diets. 2. Effect on intestinal development and lymphoid organs

• Published in: Poultry science Vol. 85; no. 5; pp. 870 - 877
• Main Authors: Fasina, Y.O, Classen, H.L, Garlich, J.D, Black, B.L, Ferket, P.R, Uni, Z, Olkowski, A.A
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.05.2006
• Subjects: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; bursa of Fabricius; cecum; Dose-Response Relationship, Drug; intestinal crypts; Intestinal Mucosa - drug effects; Intestinal Mucosa - growth & development; Intestinal Mucosa - pathology; Intestinal Mucosa - ultrastructure; Intestines - anatomy & histology; Intestines - growth & development; Intestines - pathology; Intestines - ultrastructure; jejunum; Organ Size - drug effects; Plant Lectins - administration & dosage; Plant Lectins - pharmacology; Random Allocation; Soybean Proteins - administration & dosage; Soybean Proteins - pharmacology; spleen; thymus gland; Thymus Gland - anatomy & histology; Thymus Gland - growth & development; Thymus Gland - pathology; Thymus Gland - ultrastructure; turkey feeding; Turkeys - anatomy & histology; Turkeys - physiology; villi
• ISSN: 0032-5791; 1525-3171
• DOI: 10.1093/ps/85.5.870

Lectins are capable of altering intestinal morphology by binding to and disrupting the intestinal brush border membrane. They are also known to alter the weight of lymphoid organs. Therefore, we evaluated the effect of soybean lectin (SBL) on intestinal morphology and lymphoid organ weights of poults fed diets containing SBL. Dietary treatments evaluated in this study included a cornstarch and casein-based control (lectin-free) semipurified diet (PD) and semipurified diets containing 0.024 or 0.048% SBL (PDL and PDH, respectively). Experimental diets were fed from hatch to 14 d. Morphological evaluation of the intestine involved measurement of the villi height and perimeter, crypt depth, villus:crypt, and thickness of the muscle layer in the jejunum. Intestinal physical characteristics were also determined by measuring intestinal weight, length, and volume. Results indicated that 0.048% SBL in PDH increased villus:crypt and reduced total intestinal length in turkey poults. In addition, both the 0.024 and 0.048% dietary SBL levels reduced thymus weights. It was concluded that dietary SBL up to 0.048% enhanced intestinal development by increasing villus:crypt, but might alter the structural integrity of lymphoid organs.