Vitiligo

• Published in: Journal of the American Academy of Dermatology Vol. 38; no. 5; pp. 647 - 668
• Main Author: Kovacs, Stephen O.
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.05.1998; Elsevier
• Subjects: Adrenal Cortex Hormones - therapeutic use; Autoimmune Diseases - pathology; Biological and medical sciences; Cell Death; Cosmetics - therapeutic use; Dermatology; Disease Susceptibility; Furocoumarins - therapeutic use; Humans; Medical sciences; Melanins - biosynthesis; Melanocytes - metabolism; Melanocytes - pathology; Peripheral Nervous System Diseases - complications; Pigmentary diseases of the skin; PUVA Therapy; Skin Transplantation; Vitiligo - etiology; Vitiligo - genetics; Vitiligo - immunology; Vitiligo - pathology; Vitiligo - psychology; Vitiligo - therapy; Human; Symptomatology; Skin disease; Vitiligo; Pigmentation disorder; Treatment; Pathogenesis; Review; Melanogenesis; Epidemiology

The destruction of melanocytes is the cause of depigmented maculae that clinically represent the disease vitiligo . Although the cause is unknown, various theories such as the autoimmune, autocytotoxic, and neural hypotheses have been proposed. Extensive research has provided numerous answers regard...