Vitiligo
The destruction of melanocytes is the cause of depigmented maculae that clinically represent the disease vitiligo . Although the cause is unknown, various theories such as the autoimmune, autocytotoxic, and neural hypotheses have been proposed. Extensive research has provided numerous answers regard...
Saved in:
Published in | Journal of the American Academy of Dermatology Vol. 38; no. 5; pp. 647 - 668 |
---|---|
Main Author | |
Format | Journal Article |
Language | English |
Published |
New York, NY
Mosby, Inc
01.05.1998
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The destruction of melanocytes is the cause of depigmented maculae that clinically represent the disease
vitiligo . Although the cause is unknown, various theories such as the autoimmune, autocytotoxic, and neural hypotheses have been proposed. Extensive research has provided numerous answers regarding the pathogenesis, histopathologic evidence, and treatment of vitiligo. This discussion of vitiligo summarizes the varied clinical presentations of the disease, theories attempting to explain the mechanism of melanocyte destruction, histopathologic findings, and different treatment modalities currently available. (J Am Acad Dermatol 1998;38:647-66.)
Learning Objective: At the conclusion of this learning activity, participants should be familiar with the clinical and histopathologic presentations of vitiligo, the etiologic hypotheses of the disease, and the treatment options. |
---|---|
Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 0190-9622 1097-6787 |
DOI: | 10.1016/S0190-9622(98)70194-X |