Free Vascularized Flaps for Reconstruction of the Mandible: Complications, Success, and Dental Rehabilitation

• Published in: Journal of oral and maxillofacial surgery Vol. 70; no. 7; pp. 1692 - 1698
• Main Authors: van Gemert, Johannes T.M., DMD, MD, van Es, Robert J.J., DMD, MD, PhD, Rosenberg, Antoine J.W.P., DMD, MD, PhD, van der Bilt, Andries, PhD, Koole, Ron, DMD, MD, PhD, Van Cann, Ellen M., DMD, MD, PhD
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2012; Elsevier
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Bone Plates; Bone Transplantation - methods; Carcinoma, Squamous Cell - rehabilitation; Carcinoma, Squamous Cell - surgery; Dental Implantation, Endosseous; Dental Implants; Dental Prosthesis, Implant-Supported; Dentistry; Female; Follow-Up Studies; Free Tissue Flaps - classification; Graft Survival; Humans; Male; Mandible - surgery; Mandibular Injuries - rehabilitation; Mandibular Injuries - surgery; Medical sciences; Middle Aged; Mouth Neoplasms - rehabilitation; Mouth Neoplasms - surgery; Osteotomy - methods; Otorhinolaryngology. Stomatology; Postoperative Complications; Reconstructive Surgical Procedures - methods; Retrospective Studies; Surgery; Survival Rate; Tissue and Organ Harvesting - methods; Treatment Outcome; Young Adult; Mandible; Treatment; Stomatology; Surgery; Free flap; Rehabilitation(human); Complication; Anatomical reconstruction; Tooth
• ISSN: 0278-2391; 1531-5053
• DOI: 10.1016/j.joms.2011.08.024

Purpose To evaluate complications and success of mandibular reconstruction with free fibula flaps, iliac crest flaps, and forearm flaps with reconstruction plates and to evaluate dental rehabilitation after these reconstructions. Patients and Methods Eighty-three patients with segmental mandibular defects were included. Correlation analyses were used to determine the relationship between reconstruction type and clinical parameters with recipient-site complications and success. The dental rehabilitation was evaluated in successfully reconstructed survivors. Results Multivariate analyses showed significant correlations between flap type and success ( P < .0001). Of the patients, 51 (61%) were alive 2 years after the reconstruction. Mandibular reconstruction with a free forearm flap and reconstruction plate was associated with higher complication rates at the recipient site and higher failure rates compared with reconstruction with free vascularized bone flaps. Of the 32 successfully reconstructed survivors, 14 (44%) had a complete dental rehabilitation, of which 10 had dental implants and 4 did not. Only 6 (29%) of the edentulous survivors ultimately had an implant-supported prosthesis. Conclusions Reconstruction of the mandible with a free vascularized bone flap is superior to reconstruction with a free forearm flap with a reconstruction plate. Complete dental rehabilitation was reached in fewer than half of the surviving patients.