Type I interferonopathies: Mendelian type I interferon up-regulation
Highlights • Uncontrolled up-regulation of type I interferon signaling can cause human disease. • Human monogenic type I interferonopathies are being increasingly recognized. • Therapies will likely become available to control type I interferon up-regulation.
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Published in | Current opinion in immunology Vol. 32; pp. 7 - 12 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.02.2015
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Subjects | |
Online Access | Get full text |
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Summary: | Highlights • Uncontrolled up-regulation of type I interferon signaling can cause human disease. • Human monogenic type I interferonopathies are being increasingly recognized. • Therapies will likely become available to control type I interferon up-regulation. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0952-7915 1879-0372 |
DOI: | 10.1016/j.coi.2014.10.005 |