Antileishmanial and antioxidant potential of fractions and isolated compounds from Nectandra cuspidata

• Published in: Natural product research Vol. 32; no. 23; pp. 2825 - 2828
• Main Authors: Ferreira, Lilian dos Anjos Oliveira, Oliveira, Mariana Maciel de, Faleiro, Flávia Lais, Scariot, Débora Botura, Boeing, Joana Schuelter, Visentainer, Jesuí Vergílio, Romagnolo, Mariza Barion, Nakamura, Celso Vataru, Truiti, Maria da Conceição Torrado
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.12.2018; Taylor & Francis Ltd
• Subjects: Acetic acid; Animals; Antioxidants; Antioxidants - isolation & purification; Antioxidants - pharmacology; Antiprotozoal Agents - chemistry; Antiprotozoal Agents - isolation & purification; Antiprotozoal Agents - pharmacology; Butylated hydroxytoluene; Cell Line; Cytotoxicity; Epicatechin; Ethyl acetate; lauraceae; Lauraceae - chemistry; Leishmania; Leishmania - drug effects; Leishmaniasis; Macrophages; Macrophages - drug effects; medicinal plant; Mice; Nectandra; oxidative stress; Phenols - analysis; Plant Extracts - chemistry; Plant Extracts - pharmacology; Quercetin; Toxicity; Viability; lauraceae; medicinal plant; Leishmaniasis; oxidative stress

The effects on the viability of promastigote and amastigote forms of Leishmania (Leishmania) amazonensis and citotoxicity in J774.A1 macrophages of ethanolic extract, fractions and isolated compounds that were obtained from the leaves of Nectandra cuspidata were determined. The total phenolics conte...