The Combined Use of SBRT and Immunotherapy—a Literature Review
Purpose of Review The purpose of this paper is to review all recent and relevant data regarding the combined use of immunotherapy (particularly immune checkpoint inhibitors) and radiotherapy. Recent Findings The use of radiotherapy, specifically stereotactic body radiation therapy (SBRT), and immuno...
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Published in | Current oncology reports Vol. 22; no. 12; p. 117 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
15.09.2020
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | Purpose of Review
The purpose of this paper is to review all recent and relevant data regarding the combined use of immunotherapy (particularly immune checkpoint inhibitors) and radiotherapy.
Recent Findings
The use of radiotherapy, specifically stereotactic body radiation therapy (SBRT), and immunotherapy may be synergistic in the treatment of non-small cell lung cancer (NSCLC). There have been many preclinical and clinical studies that have shown that the combination of SBRT and immunotherapy is both safe and effective. In many cases, the benefits are greater than either SBRT or immunotherapy alone. Several ongoing trials are testing the combination of SBRT and immunotherapy for the treatment of all stages of NSCLC.
Conclusion
The combined use of SBRT and immunotherapy is a promising new development. The techniques may synergistically work better than either alone. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 1523-3790 1534-6269 |
DOI: | 10.1007/s11912-020-00986-9 |