Surgery for Pancreatic Cancer

Surgical resection remains the only potentially curative therapy for pancreatic cancer, despite a high rate of systemic recurrence. Because of local invasion or distant spread, a minority of patients presenting with pancreatic cancer are candidates for surgery. Although perioperative mortality is lo...

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Bibliographic Details
Published inHematology/oncology clinics of North America Vol. 29; no. 4; p. 701
Main Author Clancy, Thomas E
Format Journal Article
LanguageEnglish
Published United States 01.08.2015
Subjects
Cholangiopancreatography, Magnetic Resonance
Endosonography
Humans
Neoplasm Recurrence, Local - epidemiology
Pancreatectomy - methods
Pancreatectomy - mortality
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - mortality
Pancreatic Neoplasms - surgery
Perioperative Period - mortality
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Tomography, X-Ray Computed
Distal pancreatectomy
Whipple
Pancreaticoduodenectomy
Pancreatic cancer
Surgery
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Summary:Surgical resection remains the only potentially curative therapy for pancreatic cancer, despite a high rate of systemic recurrence. Because of local invasion or distant spread, a minority of patients presenting with pancreatic cancer are candidates for surgery. Although perioperative mortality is low in high-volume settings, pancreatic surgery remains associated with considerable morbidity. Minimally invasive and robotic surgical techniques are increasingly used for pancreatic resection, although not always applicable to all patients. Strategies to extend the benefits of margin-negative surgical resection to more patients include surgery with vascular resection and reconstruction for locally invasive tumors, and resection after neoadjuvant therapy.
ISSN:1558-1977
DOI:10.1016/j.hoc.2015.04.001