Rare Co-existence of Squamous Cell Carcinoma with Infiltration of Renal Vein and Xanthogranulomatous Pyelonephritis

Primary renal squamous cell carcinoma is a very rare malignancy of the upper urinary tract. Most patients have history of chronic urolithiasis, analgesics abuse, radiotherapy or infection. Co-existence of SCC with xanthogranulomatous pyelonephritis is exceedingly rare with only few reports in the li...

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Bibliographic Details
Published inJournal of clinical and diagnostic research Vol. 9; no. 12; pp. ED15 - ED16
Main Authors Kanodia, K V, Vanikar, A V, Patel, R D, Nigam, L K, Trivedi, H L
Format Journal Article
LanguageEnglish
Published India JCDR Research and Publications (P) Limited 01.12.2015
JCDR Research and Publications Private Limited
Subjects
hydronephrosis
kidney
Pathology Section
pelvicalyceal system
Pelvicalyceal system
Kidney
Hydronephrosis
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Summary:Primary renal squamous cell carcinoma is a very rare malignancy of the upper urinary tract. Most patients have history of chronic urolithiasis, analgesics abuse, radiotherapy or infection. Co-existence of SCC with xanthogranulomatous pyelonephritis is exceedingly rare with only few reports in the literature. We report a case of a 60-year-old male presented with right flank pain and mild tenderness of abdomen. Computed tomography of the abdomen revealed gross hydronephrosis with parenchymal thinning and irregular thick enhancing wall of pelvicalyceal system with multiple calculi in right kidney. Right renal vein appeared distended, filled with hypo dense material. Right nephrectomy was performed and sent for pathological examination. Histological evaluation revealed keratinizing squamous cell carcinoma with infiltration of renal vein and xanthogranulomatous pyelonephritis.
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2015/14908.6924