Allergic Constitution Theory of Chinese Medicine and its Assessment Criterion and Related Studies

• Published in: Chinese journal of integrative medicine Vol. 21; no. 9; pp. 716 - 720
• Main Author: 王济 王停 李英帅 李玲孺 郑燕飞 王琦
• Format: Journal Article
• Language: English
• Published: Beijing Chinese Association of Traditional and Western Medicine 01.09.2015
• Subjects: Academic Exploration; Animals; Gene Expression Profiling; Humans; Hypersensitivity - epidemiology; Hypersensitivity - genetics; Hypersensitivity - psychology; Hypersensitivity - therapy; Medicine; Medicine & Public Health; Medicine, Chinese Traditional; 中国; 学说; 生活质量; 生理机能; 药品; 评价标准; 过敏体质; 过敏性疾病; epidemiological survey; prevention and cure; criterion; allergic constitution; gene expression
• ISSN: 1672-0415; 1993-0402
• DOI: 10.1007/s11655-014-1996-y

Constitution factor plays an important role in the occurrence, development, and transformation of diseases. The occurrence of allergic diseases is mainly caused by the disorganized physiological function and suitability regulation of patients, except for their exposure to outside allergens. Moreover, it represents susceptibility and hypersensitivity to allergens. The currant study expresses the concept of allergic constitution from the perspective of Chinese medicine （CM） and presents the criterion of allergic constitution. In addition, the distribution of allergic constitution in population, its factors, and its relation to health-related quality of life （HRQOL） were investigated. The HRQOL scores of allergic constitution were found to be lower than those of the Pinghe constitution. After making a study on the gene expression profile of allergic constitution, the characteristics of up-regulated or down-regulated genes were found. Finally, CM drug was researched and developed to improve allergic constitution. Based on clinical trials and animal experiments, CM is found to have good regulatory effects on allergic constitution.