Malignant fibrous histiocytoma of maxillary alveolar ridge extending to the hard palate

• Published in: Journal of cancer research and therapeutics Vol. 10; no. 2; p. 422
• Main Authors: Kasat, Vikrant O, Saluja, Harish, Rudagi, Bhimmapa M, Kalburge, Jitendra V, Sachdeva, Shivani
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.04.2014; Medknow Publications & Media Pvt. Ltd
• Subjects: Case studies; Diagnosis; Diseases; Female; Head and neck cancer; Histiocytoma, Malignant Fibrous - diagnostic imaging; Histiocytoma, Malignant Fibrous - pathology; Histiocytoma, Malignant Fibrous - surgery; Humans; Maxilla - pathology; Maxilla - surgery; Maxillary Neoplasms - diagnostic imaging; Maxillary Neoplasms - pathology; Maxillary Neoplasms - surgery; Middle Aged; Neoplasm Invasiveness; Palate; Palate, Hard - pathology; Palate, Hard - surgery; Radiography; Sarcoma
• ISSN: 0973-1482; 1998-4138
• DOI: 10.4103/0973-1482.136678

Malignant fibrous histiocytoma (MFH) is the most common soft-tissue sarcoma occurring in adults. This entity was first described by O'Brian and Stout in 1964. Apart from the soft-tissues, this tumor has been reported to occur in all other parts of the body including bone. It has male predilection and is usually noticed in the fifth to seventh decades of life. It commonly affects extremities and retroperitoneum, whereas involvement of the head and neck region is comparatively rare. However, when the head and neck region is affected, the most common sites are the maxillary sinus and the nasal cavity, in which case, later involvement of the maxillary alveolar bone can happen. The oral cavity is a relatively less common site for MFH. This article describes clinical, computed tomographic and microscopic features of a MFH of the maxillary alveolar ridge extending to the hard palate in a 46-year-old female patient. Histogenesis, advanced imaging features, differential diagnosis, and management of MFH are also discussed.