Low-dose methotrexate therapy for cutaneous vasculitis of rheumatoid arthritis

A patient with classic rheumatoid arthritis who developed leukocytoclastic vasculitis is described. Low-dose methotrexate produced prompt healing of the skin lesions. After discontinuation of methotrexate, the lesions recurred, with resolution after a second course of the drug. Methotrexate may be u...

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Bibliographic Details
Published inJournal of the American Academy of Dermatology Vol. 17; no. 2; pp. 355 - 359
Main Authors Upchurch, Katherine S., Heller, Kim, Bress, Norman M.
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 01.08.1987
Elsevier
Subjects
Aged
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - drug therapy
Biological and medical sciences
Bones, joints and connective tissue. Antiinflammatory agents
Humans
Male
Medical sciences
Methotrexate - administration & dosage
Methotrexate - therapeutic use
Pharmacology. Drug treatments
Skin - pathology
Skin Diseases - drug therapy
Skin Diseases - etiology
Skin Diseases - pathology
Vasculitis - complications
Vasculitis - drug therapy
Vasculitis - pathology
Human
Chemotherapy
Skin disease
Treatment
Vasculitis
Low dose
Rheumatoid arthritis
Diseases of the osteoarticular system
Vascular disorders of the skin
Skin
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Summary:A patient with classic rheumatoid arthritis who developed leukocytoclastic vasculitis is described. Low-dose methotrexate produced prompt healing of the skin lesions. After discontinuation of methotrexate, the lesions recurred, with resolution after a second course of the drug. Methotrexate may be useful in the treatment of cutaneous vasculitis associated with rheumatoid arthritis.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0190-9622
1097-6787
DOI:10.1016/S0190-9622(87)70212-6