Reduction in the frequency of N-methyl- N-nitrosourea-induced somatic mutations in Tradescantia by pretreatment with low doses of alkylating agents

Treatment of Tradescantia cuttings with sub-mutagenic doses of N-methyl- N-nitrosourea (MNU), N-ethyl- N-nitrosourea and methyl methanesulphonate before challenging doses of MNU reduced the frequency of somatic mutations in stamen hairs as compared with the effect of challenging dose alone. The high...

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Bibliographic Details
Published inMutation research Vol. 122; no. 2; pp. 229 - 234
Main Authors Velemínský, Jiří, Gichner, Tomáš, Šatava, Jan
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.01.1983
Subjects
Alkylating Agents - pharmacology
DNA Repair - drug effects
Methylnitrosourea - antagonists & inhibitors
Mutation - drug effects
Nitrosourea Compounds - antagonists & inhibitors
plant damage
plant health
Plants
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Summary:Treatment of Tradescantia cuttings with sub-mutagenic doses of N-methyl- N-nitrosourea (MNU), N-ethyl- N-nitrosourea and methyl methanesulphonate before challenging doses of MNU reduced the frequency of somatic mutations in stamen hairs as compared with the effect of challenging dose alone. The highest response was about a 50% reduction in the mutagenic effect of the challenge dose.
ISSN:0165-7992
0027-5107
DOI:10.1016/0165-7992(83)90064-7