Occupational and environmental risks in and around a smelter in northern Sweden IV. Chromosomal aberrations in workers exposed to lead

A significantly increased frequency of chromosomal aberrations was found among lead‐exposed workers at the Rönnskär smelter in northern Sweden. The frequency of aberrations showed a correlation with lead exposure as measured by the blood levels of lead. Strong individual variations were found. No sy...

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Bibliographic Details
Published inHereditas Vol. 88; no. 2; pp. 263 - 267
Main Authors NORDENSON, I., BECKMAN, G., BECKMAN, L., NORDSTRÖM, S.
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.07.1978
Subjects
Aminolevulinic Acid - blood
Chromatids
Chromosome Aberrations
Environmental Exposure
Humans
Lead - blood
Lead Poisoning - genetics
Male
Smoking - complications
Sweden
Sweden
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Summary:A significantly increased frequency of chromosomal aberrations was found among lead‐exposed workers at the Rönnskär smelter in northern Sweden. The frequency of aberrations showed a correlation with lead exposure as measured by the blood levels of lead. Strong individual variations were found. No synergistic effect of smoking was observed. Correlations were found between (chromosome and chromatid) breaks and gaps, which lends further support to the notion that gaps may be useful as indicators of genotoxic agents.
Bibliography:ark:/67375/WNG-H9M1BPHG-H
istex:083CBBC0A90173EFD256696FD641B1D72F22430F
ArticleID:HRD21628
ISSN:0018-0661
1601-5223
DOI:10.1111/j.1601-5223.1978.tb01628.x