Effect of Grape Seed Oil Supplementation on Plasma Lipid Profiles in Rats

• Published in: Food science and biotechnology Vol. 19; no. 1; pp. 249 - 252
• Main Authors: Kim, D.J., National Institute of Crop Science, RDA, Suwon, Republic of Korea, Jeon, G.U., Chungbuk National University, Cheongju, Republic of Korea, Sung, J.H., Chungbuk National University, Cheongju, Republic of Korea, Oh, S.K., National Institute of Crop Science, RDA, Suwon, Republic of Korea, Hong, H.C., National Institute of Crop Science, RDA, Suwon, Republic of Korea, Lee, J.S., Chungbuk National University, Cheongju, Republic of Korea
• Format: Journal Article
• Language: English
• Published: Heidelberg The Korean Society of Food Science and Technology 01.02.2010; 한국식품과학회
• Subjects: ACEITE DE SOJA; BACKFAT; Chemistry; Chemistry and Materials Science; Food Science; grape seed oil; HUILE DE SOJA; LARD DORSAL; lipid profile; Nutrition; RAT; RATA; RATS; Research Note; SOYBEAN OIL; TOCINO DORSAL; Vitaceae; 식품과학; grape seed oil; rat; lard; soybean oil; lipid profile
• ISSN: 1226-7708; 2092-6456
• DOI: 10.1007/s10068-010-0035-9

The purpose of the study was to investigate the comparative effects of feeding of grape seed oil (GSO), soybean oil (SO), and lard on plasima lipid profile in rats. Lard fed diets increased body weight gain in rats and resulted in negative effects on lipoprotein metabolism. However, the GSO fed rats had a significant reduction in total cholesterol (TC, 60.6 mg/dL), low density lipoprotein cholesterol (LDLC, 16.8 mg/dL), and atherogenic index (AI, 0.9), and the ratio of high density lipoprotein cholesterol (HDLC) to TC (0.5) was significantly higher than those of SO and lard groups. These data suggest that GSO supplementation has significant health benefits through favorable alterations in plasma lipid profiles compared to SO and lard fed rats. GSO may be good dietary oil and may provide health benefits in hyperlipidemia and related complications.