Dietary exposure to acrylamide in adolescents from a Canadian urban center

• Published in: Food and chemical toxicology Vol. 57; pp. 75 - 83
• Main Authors: Normandin, Louise, Bouchard, Michèle, Ayotte, Pierre, Blanchet, Carole, Becalski, Adam, Bonvalot, Yvette, Phaneuf, Denise, Lapointe, Caroline, Gagné, Michelle, Courteau, Marilène
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.07.2013; Elsevier
• Subjects: Acrylamide; Acrylamide - toxicity; acrylamides; Adolescent; Adolescents; Biological and medical sciences; breakfast cereals; Canada; Canadians; Child; Diet; Diet Records; dietary exposure; Dietary intake; Dietary survey; Female; Food analysis; Food Analysis - methods; Food Contamination; food frequency questionnaires; Food Handling - methods; food intake; food records; French fries; genotoxicity; Humans; Liquid chromatography-mass spectrometry; Male; Medical sciences; Nutrition Surveys; potato chips; Solanum tuberosum; Surveys and Questionnaires; Toxicology; Urban Population; Canada; North America; America; Canada, Quebec, Montreal; Acrylamide; MOE; Dietary survey; Liquid chromatography-mass spectrometry; JEFCA; Dietary intake; Adolescents; Food analysis; LC–MS/MS; LOQ; Human; Liquid chromatography; Exposure; Urban area; Feeding; Survey; Food intake; Adolescent; Mass spectrometry; Food
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/j.fct.2013.03.005

•Dietary intake of acrylamide was estimated in adolescents from a 2-day food diary and a food frequency questionnaire.•Deep-fried french fries consumption contributed the most to daily acrylamide intake.•The highest acrylamide contents were recorded in deep-fried french fries and potato chips.•Total dietary intake of acrylamide in adolescents of our study was similar to that of other studies.•Margins of exposure based on genotoxic benchmark dose limits were estimated to be low in high-consumer adolescents. The distribution of acrylamide in food items frequently consumed by Canadian adolescents was determined along with estimates of their contribution to the overall dietary intake of acrylamide. A total of 196 non-smoking adolescents (10–17years old) were recruited in Montreal Island population, Canada. Participants were invited to fill out a 2-day food diary and a food frequency questionnaire over the last month. 146 samples of foods most frequently consumed by participants were analyzed for acrylamide contents. The highest acrylamide contents were measured in deep-fried french fries and potato chips (mean±SD: 1053±657 and 524±276ng/g respectively). On the basis of the 2-day food diary, median total daily intake of acrylamide was estimated at 0.29μg/kgbw/d, as compared to 0.17μg/kgbw/d on the basis of the food frequency questionnaire. These values are similar to those reported in comparable populations. Deep-fried french fries consumption contributed the most to daily acrylamide intake (50%) followed by potato chips (10%), oven-baked french fries (8%) and breakfast cereals (8%). Margins of exposure based on genotoxic benchmark dose limits were estimated to be low (≈<100) in high-consumer adolescents, indicating the need to continue efforts to reduce dietary acrylamide exposure.