Corticosteroid treatment of behaviour, language and motor regression in childhood disintegrative disorder

Abstract Childhood disintegrative disorder (CDD) (ICD-10 F84.3) is defined by a period of normal development before onset followed by gradual loss of previously acquired skills with the development of characteristic abnormalities of social, communicative and behavioural functioning. We report two ch...

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Published inEuropean journal of paediatric neurology Vol. 13; no. 4; pp. 367 - 369
Main Authors Mordekar, Santosh R, Prendergast, Michael, Chattopadhyay, Arup K, Baxter, Peter S
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.07.2009
Subjects
Adrenal Cortex Hormones - therapeutic use
Child Development Disorders, Pervasive - complications
Child Development Disorders, Pervasive - drug therapy
Child Development Disorders, Pervasive - psychology
Child, Preschool
Childhood disintegrative disorder
Corticosteroid
Developmental Disabilities - drug therapy
Developmental Disabilities - etiology
Female
Humans
Language
Language Development Disorders - drug therapy
Language Development Disorders - etiology
Male
Movement Disorders - drug therapy
Movement Disorders - etiology
Neurology
Pediatrics
Severity of Illness Index
Corticosteroid
Childhood disintegrative disorder
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Summary:Abstract Childhood disintegrative disorder (CDD) (ICD-10 F84.3) is defined by a period of normal development before onset followed by gradual loss of previously acquired skills with the development of characteristic abnormalities of social, communicative and behavioural functioning. We report two children with apparent CDD, who showed amelioration of behaviour, language and motor regression after corticosteroid treatment.
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ISSN:1090-3798
1532-2130
DOI:10.1016/j.ejpn.2008.06.001