Factors affecting sleep quality in patients with psoriasis

Poor sleep quality adversely affects quality of life in patients with psoriasis. However, the factors impairing sleep in these patients have not been well described. We reviewed the available literature linking sleep quality and psoriasis to elucidate factors that interfere with sleep. Pruritus, dep...

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Bibliographic Details
Published inJournal of the American Academy of Dermatology Vol. 63; no. 1; pp. 114 - 123
Main Authors Gowda, Smitha, MD, Goldblum, Orin M., MD, McCall, W. Vaughn, MD, MS, Feldman, Steven R., MD, PhD
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 01.07.2010
Elsevier
Subjects
Biological and medical sciences
Depression - etiology
Dermatology
Fatigue - etiology
Humans
itch
Medical sciences
Pain - etiology
Pruritus - etiology
psoriasis
Psoriasis - complications
Psoriasis - physiopathology
Psoriasis. Parapsoriasis. Lichen
Quality of Life
sleep
Sleep - physiology
Sleep Apnea, Obstructive - etiology
Sleep Wake Disorders - etiology
obstructive sleep apnea
itch
willingness to pay
IL
TNF
sleep
WTP
dermatology
tumor necrosis factor
psoriasis
interleukin
OSA
substance P
SP
Human
Skin disease
Psoriasis
Dermatology
Quality
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Summary:Poor sleep quality adversely affects quality of life in patients with psoriasis. However, the factors impairing sleep in these patients have not been well described. We reviewed the available literature linking sleep quality and psoriasis to elucidate factors that interfere with sleep. Pruritus, depression, pain, and obstructive sleep apnea may be likely sources of sleep impairment in patients with psoriasis. Fatigue resulting from sleep interference may also be implicated in this relationship. Pruritus, depression, and pain interfere with sleep quality by increasing nocturnal awakenings and sleep fragmentation. Obstructive sleep apnea may occur in a greater percentage of patients with psoriasis than control populations. Factors associated with psoriasis appear to have similarities in their cytokine and neuropeptide profiles. Moreover, these variables are complex and interconnected. Further study and awareness of potential factors impacting sleep in patients with psoriasis may provide new avenues for treatment of recalcitrant disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2009.07.003