Clinicopathologic factors influencing the accuracy of EUS for superficial esophageal carcinoma

• Published in: World journal of gastroenterology : WJG Vol. 20; no. 20; pp. 6322 - 6328
• Main Authors: Jung, Jung Im, Kim, Gwang Ha, I, Hoseok, Park, Do Youn, Kim, Tae Kyun, Cho, Young Hwa, Sung, Yong Wan, Choi, Mun Ki, Lee, Bong Eun, Song, Geun Am
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 28.05.2014
• Subjects: Accur; Adult; Aged; Aged, 80 and over; cancer; Carcinoma - diagnosis; Carcinoma - diagnostic imaging; Catheterization; Clinical Trials Study; Endoscopic; Endoscopy; Endosonography; Esophageal; Esophageal Neoplasms - diagnosis; Esophageal Neoplasms - diagnostic imaging; Female; Humans; Male; Medical Records; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Reproducibility of Results; Republic of Korea; Retrospective Studies; ultrasonography; Accuracy; Endoscopic ultrasonography; Esophageal cancer
• ISSN: 1007-9327; 2219-2840
• DOI: 10.3748/wjg.v20.i20.6322

AIM:To identify clinicopathologic factors influencing the accuracy of a high-frequency catheter probe endoscopic ultrasonography(EUS)for superficial esophageal carcinomas(SECs).METHODS:A total of 126 patients with endoscopically suspected SEC,who underwent EUS and curative treatment at Pusan National University Hospital during2005-2013,were enrolled.We reviewed the medical records of the 126 patients and compared EUS findings with histopathologic results according to clinicopathologic factors.RESULTS:A total of 114 lesions in 113 patients were included in the final analysis.The EUS assessment of tumor invasion depth was accurate in 78.9%(90/114)patients.Accuracy did not differ according to histologic type,tumor differentiation,tumor location,or macroscopic shape.However,accuracy significantly decreased for tumors≥3 cm in size(P=0.002).Overestimation and underestimation of the invasion depth occurred for 11(9.6%)and 13 lesions(11.4%),respectively.In multivariate analyses,tumor size≥3 cm was the only factor significantly associated with EUS accuracy(P=0.031),and was specifically associated with the underestimation of invasion depth.CONCLUSION:EUS using a high-frequency catheter probe generally provides highly accurate assessments of SEC invasion depth,but its accuracy decreases for tumors≥3 cm.