Estimated impact of multiple conceptuses per follicle on fecundity in the bitch

• Published in: Theriogenology Vol. 102; pp. 108 - 115
• Main Authors: Steckler, D., De Cramer, K.G.M., Nöthling, J.O.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.10.2017
• Subjects: Animals; Bitch; Corpus luteum; Corpus Luteum - physiology; Dogs - physiology; Female; Fertility; Monozygotic twins; Multi-ovular follicles; Oocyte; Ovarian Follicle - physiology; Pregnancy; Pregnancy, Animal - physiology; Multi-ovular follicles; Corpus luteum; Bitch; Fertility; Monozygotic twins; Oocyte
• ISSN: 0093-691X; 1879-3231
• DOI: 10.1016/j.theriogenology.2017.07.006

Multiple conceptuses from one follicle due to multi-ovular follicles or monozygotic twins inflate the ratio between the numbers of conceptuses and corpora lutea and possibly the effect ascribed to experimental treatment. The aim of this study was to estimate the impact of multiple conceptuses per follicle on fecundity in the bitch. The numbers of conceptuses and corpora lutea of 105 bitches originated from 7 published experimental studies and of 132 from ovariohysterectomies done in a private practice and a welfare organisation. Ninety five bitches, producing 597 conceptuses, had at least as many conceptuses as corpora lutea; 83 had as many, 10 had one more and 2 had 2 more. Bootstrap resampling on these 95 bitches let us to conclude that 12.6% of bitches are expected to produce more oocytes that are each capable of yielding a conceptus than the number of follicles that ovulate and that 2.35% of conceptuses are expected to be in excess of the number of follicles that ovulate. Applying the results of the current study to 2 earlier studies showed that multiple conceptuses from one follicle may, at maximum, have increased the effect ascribed to prostatic fluid by 0.022 and 0.024 conceptuses per corpus luteum, which is minor in relation to the magnitude of the ascribed effects of 0.34 and 0.22 conceptuses per corpus luteum. The number of conceptuses relative to the number of corpora lutea provides a valid and precise measurement of fertility in the bitch. •The aim of this study was to estimate the impact of multiple conceptuses per follicle on fecundity in the bitch.•12.6% of bitches may produce more oocytes, each capable of yielding a conceptus more than the number of ovulated follicles.•Results also demonstrate that 2.35% of conceptuses are expected to be in excess of the number of follicles that ovulate.•The number of conceptuses relative to the number of corpora lutea is a precise measurement of the fertility in the bitch.