Synchronous breast implant associated anaplastic large cell lymphoma (BIA-ALCL) and silicone induced granuloma of breast implant capsule (SIGBIC): What to learn

• Published in: Radiology case reports Vol. 15; no. 10; pp. 1736 - 1742
• Main Author: Fleury, Eduardo de Faria Castro
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.10.2020; Elsevier
• Subjects: Anaplastic large cell lymphoma; Breast Imaging; Breast implants; Seroma; Silicone; SIGBIC; Seroma; Anaplastic large cell lymphoma; BMR; Silicone; Breast implants; BIA-ALCL; PDMS; PDMS, polydimethylsiloxane; BIA-ALCL, breast implant associated anaplastic large cell lymphoma; BMR, breast magnetic resonance; SIGBIC, silicone induced granuloma of breast implant capsule
• ISSN: 1930-0433; 1930-0433
• DOI: 10.1016/j.radcr.2020.07.017

We recently described silicone induced granuloma of breast implant capsule (SIGBIC) as an implant capsule illness related to intact silicone breast implants. The precursor to SIGBIC development is gel bleeding/shedding from the implant shell/interior content. Currently, although the literature widely discussed the pathogenesis of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), the trigger point for its development is still a black-box. In this case report, we report a 46-year-old woman with SIGBIC diagnosis in her right breast and BIA-ALCL in her left breast, diagnosed with ultrasound and breast magnetic resonance. Microscopy confirmed silicone bleeding from the implant surface/ content. The imaging findings reported that SIGBIC and BIA-ALCL were similar; however, BIA-ALCL had an intracapsular collection.