Update on thyroid-associated Ophthalmopathy with a special emphasis on the ocular surface

Thyroid-associated ophthalmopathy (TAO) is a condition associated with a wide spectrum of ocular changes, usually in the context of the autoimmune syndrome, Graves' disease. In this topical review, we attempted to provide a roadmap of the recent advances in current understanding the pathogenesi...

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Published inClinical diabetes and endocrinology Vol. 2; no. 1; p. 19
Main Authors Novaes, Priscila, Diniz Grisolia, Ana Beatriz, Smith, Terry J
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 16.11.2016
BioMed Central
Subjects
Eye diseases
Proteins
Review
Thyrotropin
Ophthalmopathy
Orbit
Ocular surface
Graves’ disease
Thyroid
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Summary:Thyroid-associated ophthalmopathy (TAO) is a condition associated with a wide spectrum of ocular changes, usually in the context of the autoimmune syndrome, Graves' disease. In this topical review, we attempted to provide a roadmap of the recent advances in current understanding the pathogenesis of TAO, important aspects of its clinical presentation, its impact on the ocular surface, describe the tissue abnormalities frequently encountered, and describe how TAO is managed today. We also briefly review how increased understanding of the disease should culminate in improved therapies for patients with this vexing condition.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:2055-8260
2055-8260
DOI:10.1186/s40842-016-0037-5