Effect of an Anticalculus Toothpaste Containing Pyrophosphate on Pyrophosphatase Activity and the State of Calcium Phosphate in Saliva

Experiments were performed to determine if a pyrophosphate-containing anticalculus toothpaste could affect certain salivary constituents involved in the mineralization of dental plaque. The findings indicated no obvious changes in acid and alkaline pyrophosphatases, ionized calcium, total calcium, i...

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Published inJournal of Nihon University School of Dentistry Vol. 35; no. 2; pp. 85 - 90
Main Authors KOONTONGKAEW, Sittichai, SURARIT, Rudee, PHANTUMVANIT, Prathip
Format Journal Article
LanguageEnglish
Published Japan Nihon University School of Dentistry 1993
Subjects
Adult
Analysis of Variance
anticalculus toothpaste
Calcium - analysis
Calcium Phosphates - analysis
Dental Calculus - prevention & control
Dentistry
Diphosphates - pharmacology
Female
Humans
Hydrogen-Ion Concentration
Male
Multivariate Analysis
phosphate
pyrophosphatase
Pyrophosphatases - antagonists & inhibitors
Pyrophosphatases - metabolism
pyrophosphate
Saliva - chemistry
Saliva - drug effects
Saliva - enzymology
salivary calcium
Single-Blind Method
Toothpastes - pharmacology
Toothpastes - therapeutic use
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Summary:Experiments were performed to determine if a pyrophosphate-containing anticalculus toothpaste could affect certain salivary constituents involved in the mineralization of dental plaque. The findings indicated no obvious changes in acid and alkaline pyrophosphatases, ionized calcium, total calcium, inorganic phosphate or pH in saliva for 1-135 min after brushing the teeth with the anticalculus toothpaste. Data obtained by brushing with the toothpaste three times daily for two weeks also confirmed these results. Our findings clearly indicate that pyrophosphate-stabilizing agents in the anticalculus toothpaste are not fully effective in the oral cavity. In addition, the pyrophosphate-containing toothpaste has no influence on the state of calcium and phosphate in saliva.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0029-0432
1884-2984
DOI:10.2334/josnusd1959.35.85