Epstein–Barr virus reactivation‐related meningoencephalitis with transverse myelitis in pregnancy

• Published in: Clinical case reports Vol. 11; no. 9; pp. e7923 - n/a
• Main Authors: Nguyen, Andrew Dang Khai, Siu, Ronald, Kleinschmidt, Grant, Sood, Bimal Prakash, Shandiz, Ehsan Esmaili
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.09.2023; John Wiley and Sons Inc; Wiley
• Subjects: Antibiotics; Antibodies; Antigens; Apheresis; Bacterial infections; Case Report; Cellular biology; Cerebrospinal fluid; Edema; Encephalitis; Epstein-Barr virus; Immunoglobulins; Infectious Diseases; Inflammatory diseases; Meningitis; meningoencephalitis; Morphology; Neurology; Pathogens; Pregnancy; Serology; Spinal cord; Steroids; Streptococcus infections; transverse myelitis; India; transverse myelitis; meningoencephalitis; Epstein–Barr virus; pregnancy
• ISSN: 2050-0904; 2050-0904
• DOI: 10.1002/ccr3.7923

Key Clinical Message Consider the differential of Epstein–Barr virus (EBV) reactivation in pregnant women who develop progressive meningoencephalitis and transverse myelitis. EBV nucleic acid amplification should be considered in immunosuppressed patients. A 32‐year‐old G10P6M3K22 pregnant female presented to a regional hospital with progressive severe neurological and behavioral deficits. Magnetic resonance revealed cervical transverse myelitis. Lumbar puncture confirmed Epstein–Barr virus (EBV) DNA on a background of IgG‐positive EBV serology. A diagnosis of EBV reactivation‐related meningoencephalitis with transverse myelitis in pregnancy was concluded.