Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil

• Published in: Brazilian Journal of Pharmaceutical Sciences Vol. 53; no. 4
• Main Authors: Damasceno, Carolina Sette Barbosa, Oliveira, Letícia Freire de, Szabo, Ellis Marina, Souza, Ângela Maria, Dias, Josiane Fatima Gaspari, Miguel, Marilis Dalarmi, Miguel, Obdúlio Gomes
• Format: Journal Article
• Language: English
• Published: Sao Paulo Universidade de Sao Paulo Faculdade de Ciencias 01.01.2017; Universidade de São Paulo, Faculdade de Ciências Farmacêuticas; Universidade de São Paulo
• Subjects: Antimicrobial agents; Antioxidant activity; Antioxidants; Biological activity; Cysts; Lauraceae; Leaves; Ocotea bicolor/Oil essential/chemical composition; Oils & fats; PHARMACOLOGY & PHARMACY; Brazil; Lauraceae; Ocotea bicolor/Oil essential/chemical composition; Antioxidant activity; Biological activity
• ISSN: 2175-9790; 1984-8250; 2175-9790
• DOI: 10.1590/s2175-97902017000417298

The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, δ-cadinene (7.39%), β-sesquiphellandrene (6.67%), β-elemene (5.41%) and α-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 μg/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (μg/mL), being toxic to the organisms in this study.