Laryngopharyngeal reflux might play a role on chronic nonspecific pharyngitis
Chronic nonspecific pharyngitis is one of the most common reasons for visits to otorhinolaryngology physicians. The underlying conditions are still unknown. The aim of this study was to investigate the role of laryngopharyngeal reflux in chronic nonspecific pharyngitis patients based on the patient’...
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Published in | European archives of oto-rhino-laryngology Vol. 267; no. 4; pp. 571 - 574 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Berlin/Heidelberg
Springer-Verlag
01.04.2010
Springer |
Subjects | |
Online Access | Get full text |
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Summary: | Chronic nonspecific pharyngitis is one of the most common reasons for visits to otorhinolaryngology physicians. The underlying conditions are still unknown. The aim of this study was to investigate the role of laryngopharyngeal reflux in chronic nonspecific pharyngitis patients based on the patient’s history and clinical examination. Fifty consecutive patients with symptoms of chronic nonspecific pharyngitis and control group of 30 healthy persons were evaluated prospectively. 14C-urea breath test was used to exclude
Helicobacter pylori
infection of gastric mucosa. All the patients and the controls were assessed by blinded same laryngologist with the use of the reflux finding score (RFS) and reflux symptoms index (RSI). Also chronic nonspecific pharyngitis patients with laryngopharyngeal reflux (LPR) were evaluated prospectively before and 6 months after b.i.d treatment with proton pump inhibitors. The RSI of the nonspecific pharyngitis group was found significantly higher than the control group (
P
< 0.01). The RFS of nonspecific pharyngitis was found significantly higher than the control group (
P
< 0.01). The reflux finding score ≥7 has been accepted as LPR; the reflux incidence was significantly higher in the nonspecific pharyngitis group than the control group (
P
< 0.01). Posttreatment RSI of nonspecific pharyngitis patients group revealed a statistically significant decrease when compared with the pretreatment RSI (
P
< 0.01). Posttreatment RFS of nonspecific pharyngitis patients also revealed a significant decrease when compared with the pretreatment RFS (
P
< 0.01). We suggest that LPR may be related to the pathogenesis of chronic nonspecific pharyngitis. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0937-4477 1434-4726 |
DOI: | 10.1007/s00405-009-1044-2 |