Viral vectors as vaccine platforms: deployment in sight

Highlights ► Viral-vectored vaccines for veterinary and human use: induction of T cell responses. ► Induction of tailored polyfunctional, site-specific and memory immune response. ► Chimpanzee adenoviruses in humans circumvent pre-existing immunity. ► Success of prime-boost regimen in clinical trial...

Full description

Saved in:
Bibliographic Details
Published inCurrent opinion in immunology Vol. 23; no. 3; pp. 377 - 382
Main Authors Rollier, Christine S, Reyes-Sandoval, Arturo, Cottingham, Matthew G, Ewer, Katie, Hill, Adrian VS
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.06.2011
Subjects
Adenovirus
Allergy and Immunology
Animals
Clinical Trials as Topic
Genetic Vectors - genetics
Human immunodeficiency virus
Humans
Treatment Outcome
Viral Vaccines - genetics
Viral Vaccines - immunology
Virus Diseases - immunology
Virus Diseases - prevention & control
Online AccessGet full text

Cover

More Information
Summary:Highlights ► Viral-vectored vaccines for veterinary and human use: induction of T cell responses. ► Induction of tailored polyfunctional, site-specific and memory immune response. ► Chimpanzee adenoviruses in humans circumvent pre-existing immunity. ► Success of prime-boost regimen in clinical trials for HIV and malaria. ► New technologies for enhancement of the vectors manufacturing and deployment.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ObjectType-Feature-1
ISSN:0952-7915
1879-0372
DOI:10.1016/j.coi.2011.03.006