Gastrulation: PARtaking of the Bottle

Gastrulation in C. elegans embryos involves ingression of individual cells, but is driven by apical constriction of the kind that promotes migration of epithelial cell sheets. Recent work shows that PAR proteins, known for their role in polarization and unequal cell division, are also associated wit...

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Bibliographic Details
Published inCurrent biology Vol. 13; no. 6; pp. R223 - R225
Main Authors Putzke, Aaron P., Rothman, Joel H.
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 18.03.2003
Subjects
Actin Cytoskeleton - metabolism
Animals
Caenorhabditis elegans - cytology
Caenorhabditis elegans - genetics
Caenorhabditis elegans - physiology
Caenorhabditis elegans Proteins - genetics
Caenorhabditis elegans Proteins - metabolism
Cell Polarity
Gastrula - cytology
Gastrula - physiology
Microtubules - metabolism
Models, Biological
Protein-Serine-Threonine Kinases - genetics
Protein-Serine-Threonine Kinases - metabolism
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Summary:Gastrulation in C. elegans embryos involves ingression of individual cells, but is driven by apical constriction of the kind that promotes migration of epithelial cell sheets. Recent work shows that PAR proteins, known for their role in polarization and unequal cell division, are also associated with the polarization that establishes this apical constriction.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(03)00155-6