Clonal serotype 1c multidrug-resistant Shigella flexneri detected in multiple institutions by sentinel-site sequencing

• Published in: Frontiers in medicine Vol. 9; p. 964640
• Main Authors: Ko, Karrie K. K., Chu, Joash Jun Keat, Lim, Kar Mun, Yingtaweesittikul, Hatairat, Huang, Wenjie, Tan, Shireen Yan Ling, Goh, Kenneth Choon Meng, Tan, Si Huei, Ng, Tong Yong, Maiwald, Matthias, Chia, Jonathan Wei Zhong, Cao, Delphine Yanhong, Tan, Yen Ee, Sim, James Heng Chiak, Koh, Tse Hsien, Nagarajan, Niranjan, Suphavilai, Chayaporn
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 01.08.2022
• Subjects: Medicine; multidrug-resistant (MDR); outbreak; Shigella flexneri; surveillance; whole-genome sequence (WGS)

Shigella flexneri is a major diarrhoeal pathogen, and the emergence of multidrug-resistant S. flexneri is of public health concern. We report the detection of a clonal cluster of multidrug-resistant serotype 1c (7a) S. flexneri in Singapore in April 2022. Long-read whole-genome sequence analysis fou...