Authors respond to qSOFA predicting outcomes in patients with infection, some lingering doubts

• Published in: The American journal of emergency medicine Vol. 35; no. 4; pp. 650 - 651
• Main Authors: Wang, Jun-Yu, Chen, Yun-Xia, Guo, Shu-Bin, Mei, Xue, Yang, Peng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2017; Elsevier Limited
• Subjects: Antibiotics; APACHE; Emergency; Emergency medical care; Enrollments; Humans; ICU; Illnesses; Infection; Infections; Lactic acid; Meds; Mortality; Organ Dysfunction Scores; Patients; Prognosis; qSOFA; Sepsis; United States > US; China; Europe; mortality; infection; ICU; MEDS; qSOFA; Infection; Meds; Mortality
• ISSN: 0735-6757; 1532-8171
• DOI: 10.1016/j.ajem.2016.12.043

Besides this, the patients with relatively severe intro-abdominal infection or accompanied contraindications of surgical treatment were also treated in ED. [...]we got a different opinion on the enrollment time point in our study. Compared with the suspected infection in the original study of qSOFA, our cohort was at the developed infection stage. [...]ED arrival may be an early time point for hospital visiting, but not an early time point for infection. Though the prognostic value of the changes of qSOFA was an attractive issue, the original study did not provide these results. Since our data was limited to the only time point of ED arrival, we could not provide these information either. [...]the illness severity of our cohort was similar to the ICU encounters of original study. [...]it was not surprise that the prognostic performance of qSOFA (0.666 vs 0.66) and SOFA (0.729 vs 0.74) in our study was very similar to that of ICU encounters in the original study. [...]a certain number of enrolled patients missed lactate values on ED arrival.