Acalculous cholecystitis associated with hemorrhagic fever with renal syndrome

• Published in: Acta clinica belgica (English ed. Online) Vol. 70; no. 5; pp. 377 - 381
• Main Author: Nicolas, J. B.
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.10.2015
• Subjects: Acalculous cholecystitis; Acalculous Cholecystitis - diagnostic imaging; Acalculous Cholecystitis - etiology; Adolescent; Endothelial dysfunction; Epidemic nephropathy; Hantavirus pulmonary syndrome; Hemorrhagic fever; Hemorrhagic Fever with Renal Syndrome - complications; Hemorrhagic Fever with Renal Syndrome - diagnosis; Humans; Male; Plasma leakage; Puumala; Ultrasonography; Plasma leakage; Hemorrhagic fever; Puumala; Endothelial dysfunction; Acalculous cholecystitis; Epidemic nephropathy; Hantavirus pulmonary syndrome
• ISSN: 1784-3286; 2295-3337
• DOI: 10.1179/2295333715Y.0000000028

Hantaviruses are responsible for various types of hemorrhagic fevers depending on the involved subtype. In Europe, Puumala virus is responsible for an epidemic nephropathy. This infection can be complicated by severe abdominal pain. A rarely reported cause of this presenting symptom is acalculous cholecystitis, which must be integrated in the clinicobiological spectrum and should not lead to a surgical sanction. Its presence seems to be correlated with the severity of the disease, whose main pathophysiological phenomenon is plasma leakage induced by a microvascular endothelial dysfunction. We report the case of a young male patient who presented with severe hantavirus infection complicated by acalculous cholecystitis.