Oxidative Stress Is Decreased in Off-pump Versus On-pump Coronary Artery Surgery

• Published in: BMB reports Vol. 39; no. 4; pp. 377 - 382
• Main Authors: Gonenc, Aymelek (Gazi University, Ankara, Turkey), E-mail: aymelek@gazi.edu.tr, Haclsevki, Aysun (Gazi University, Ankara, Turkey), Bakkaloglu, Beyhan (Guven Hospital, Ankara, Turkey), Soyagir, Aylin (Guven Hospital, Ankara, Turkey), Torun, Meral (Gazi University, Ankara, Turkey), Karagoz, Haldun (Guven Hospital, Ankara, Turkey), Simsek, Bolkan (Gazi University, Ankara, Turkey)
• Format: Journal Article
• Language: English
• Published: Korea (South) 31.07.2006
• Subjects: Aged; Case-Control Studies; Coronary artery bypass; Coronary Artery Bypass - methods; Coronary Artery Bypass, Off-Pump; ESTRES; Female; GLUTATHION PEROXYDASE; GLUTATHIONE PEROXIDASE; Glutathione Peroxidase - blood; GLUTATION PEROXIDASA; Heart-Assist Devices; Humans; Male; Malondialdehyde; Malondialdehyde - blood; Middle Aged; OXIDACION; OXIDATION; Oxidative Stress; OXYDATION; STRESS; SUPEROXIDE DISMUTASE; Superoxide Dismutase - blood; SUPEROXIDO DISMUTASA; SUPEROXYDE DISMUTASE
• ISSN: 1225-8687; 1976-6696; 0219-1024
• DOI: 10.5483/bmbrep.2006.39.4.377

Oxidative stress occurs in patients undergoing coronary artery bypass operation. The aim of this study was to investigate the difference in oxidative stress in off-pump versus on-pump coronary artery bypass surgery. In the present study, in serial blood samples, plasma malondialdehyde (MDA) as index of lipid peroxidation, red blood cells glutathione peroxidase (GPx) and superoxide dismutase (SOD) were measured to compare the extent of oxidative stress in 30 patients undergoing OPCAB (off-pump coronary artery bypass grafting), 12 patients undergoing CABG (on-pump coronary artery bypass grafting) and 18 healthy controls.