CircRNA Is a Rising Star in Researches of Ocular Diseases

• Published in: Frontiers in cell and developmental biology Vol. 8; p. 850
• Main Authors: Zhang, Chengshou, Hu, Jianghua, Yu, Yibo
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 03.09.2020
• Subjects: Cell and Developmental Biology; circular RNA; microRNA sponge; noncoding RNA; ocular diseases; ophthalmology

A newly rediscovered subclass of noncoding RNAs, circular RNAs (circRNAs), is produced by a back-splicing mechanism with a covalently closed loop structure. They not only serve as the sponge for microRNAs (miRNAs) and proteins but also regulate gene expression and epigenetic modification, translate...