Nine modalities to report d -dimer concentration: how many is too many?

[...]sudden death is the initial clinical presentation of 25% of PTE patients [2]. [...]in PTE, up to 80% of deaths occur within 2.5 hours into the admission [3]. d-dimer (DD) is the best recognized biomarker for the initial assessment of suspected venous thromboembolism (VTE) [4]. d-dimer is a smal...

Full description

Saved in:
Bibliographic Details
Published inThe American journal of emergency medicine Vol. 30; no. 6; pp. 1007 - 1008
Main Author Koracevic, Goran P., MD, PhD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.2012
Elsevier Limited
Subjects
Biomarkers - blood
Coagulation
Emergency
Emergency medical care
Fibrin Fibrinogen Degradation Products - analysis
Health risk assessment
Humans
Medical treatment
Pulmonary Embolism - blood
Reference Values
Thromboembolism
Venous Thromboembolism - blood
Online AccessGet full text

Cover

More Information
Summary:[...]sudden death is the initial clinical presentation of 25% of PTE patients [2]. [...]in PTE, up to 80% of deaths occur within 2.5 hours into the admission [3]. d-dimer (DD) is the best recognized biomarker for the initial assessment of suspected venous thromboembolism (VTE) [4]. d-dimer is a small peptide fragment, an end product of fibrinogen and cross-linked fibrin degradation, and the name DD is adequate because DD consists of 2 cross-linked D fragments of fibrinogen [5]. d-dimer points to activated coagulation and fibrinolysis. [...]DD came to stay as a very important marker of coagulation and fibrinolysis, with high negative predictive value in VTE and also in the acute aortic dissection.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2012.03.023