Magnetic resonance imaging based functional imaging in paediatric oncology

Abstract Imaging is central to management of solid tumours in children. Conventional magnetic resonance imaging (MRI) is the standard imaging modality for tumours of the central nervous system (CNS) and limbs and is increasingly used in the abdomen. It provides excellent structural detail, but impar...

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Bibliographic Details
Published inEuropean journal of cancer (1990) Vol. 72; pp. 251 - 265
Main Authors Manias, Karen A, Gill, Simrandip K, MacPherson, Lesley, Foster, Katharine, Oates, Adam, Peet, Andrew C
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.02.2017
Elsevier Science Ltd
Subjects
Biomarkers, Tumor - analysis
Blood flow
Central nervous system
Central Nervous System Neoplasms - diagnostic imaging
Child
Children
Diffusion magnetic resonance imaging
Diffusion Magnetic Resonance Imaging - methods
Diffusion tensor imaging
Functional magnetic resonance imaging
Hematology, Oncology and Palliative Medicine
Humans
Imaging techniques
Magnetic properties
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Magnetic Resonance Spectroscopy
Metabolites
Metastases
Neoplasms
Neoplasms - diagnostic imaging
NMR
Nuclear magnetic resonance
Paediatrics
Pediatrics
Perfusion
Perfusion imaging
Resonance
Solid tumors
Tumors
Magnetic resonance spectroscopy
Magnetic resonance imaging
Perfusion imaging
Diffusion magnetic resonance imaging
Functional magnetic resonance imaging
Paediatrics
Neoplasms
Diffusion tensor imaging
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Summary:Abstract Imaging is central to management of solid tumours in children. Conventional magnetic resonance imaging (MRI) is the standard imaging modality for tumours of the central nervous system (CNS) and limbs and is increasingly used in the abdomen. It provides excellent structural detail, but imparts limited information about tumour type, aggressiveness, metastatic potential or early treatment response. MRI based functional imaging techniques, such as magnetic resonance spectroscopy, diffusion and perfusion weighted imaging, probe tissue properties to provide clinically important information about metabolites, structure and blood flow. This review describes the role of and evidence behind these functional imaging techniques in paediatric oncology and implications for integrating them into routine clinical practice.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0959-8049
1879-0852
DOI:10.1016/j.ejca.2016.10.037