Generation of a human induced pluripotent stem cell (iPSC) line (JUCTCi011-A) from skin fibroblasts of a healthy Jordanian male subject

Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast...

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Published inStem cell research Vol. 48; p. 101923
Main Authors Ababneh, Nidaa A., Al-Kurdi, Ban, Ali, Dema, Barham, Raghda, Sharar, Nour, Mrahleh, Mairvat M., Salah, Bareqa, Awidi, Abdalla
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.10.2020
Elsevier
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Summary:Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast cells, expressed pluripotency markers and showed a differentiation potential into three germ layers as demonstrated by immunostaining and flow cytometry. This generated cell line can be used in disease modeling studies, to serve as a healthy control line and to help in developing novel therapeutic strategies for patients with hereditary neuromuscular diseases.
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ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2020.101923