Novel oligopeptide nanoprobe for targeted cancer cell imaging

• Published in: RSC advances Vol. 8; no. 54; pp. 30887 - 30893
• Main Authors: Ding, Wen-Qiang, Qin, Si-Yong, Cheng, Yin-Jia, Ma, Yi-Han, Zhang, Ai-Qing
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 01.01.2018; The Royal Society of Chemistry
• Subjects: Aspartic acid; Cancer; Chemistry; Fluorescence; fluorescent dyes; Glycine; hydrogen bonding; Hydrogen bonds; image analysis; nanomaterials; neoplasm cells; neoplasms; Phenylalanine; Tryptophan

Here we designed and constructed a tryptophan-phenylalanine-phenylalanine-tryptophan (WFFW) tetrapeptide, which generated photostable and tunable fluorescence emission signals from 340 nm to 500 nm. The WFFW tetrapeptide could self-assemble into a spherical nanostructure with enhanced fluorescence i...