The matrix of fruit & vegetables modulates the gastrointestinal bioaccessibility of polyphenols and their impact on dietary protein digestibility

• Published in: Food chemistry Vol. 240; pp. 314 - 322
• Main Authors: Dufour, Claire, Loonis, Michèle, Delosière, Mylène, Buffière, Caroline, Hafnaoui, Noureddine, Santé-Lhoutellier, Véronique, Rémond, Didier
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2018; Elsevier
• Subjects: Dietary Proteins; Digestion; Food and Nutrition; Fruit; Fruit & vegetables; Gastrointestinal digestion; Life Sciences; Minipig; Phenolic compounds; Polyphenols; Protein; Vegetables; Gastrointestinal digestion; Minipig; Phenolic compounds; Fruit & vegetables; Protein; phenolic compounds; minipig; vegetables; fruit; gastrointestinal digestion; protein
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2017.07.104

•First in vivo study (pig) dealing with polyphenol bioaccessibility in the gastric tract.•Polyphenol bioaccessibility is low in stomach after F&V or extract ingestion (3.1 or 1.5%).•Plant effect: polyphenol diffusion from apple>diffusion from artichoke and plum.•Polyphenol bioaccessibility at the ileum in agreement with that for ileostomists.•The phenolic extract, but not F&V, decreased the speed and efficiency of protein digestion. Fruit and vegetables (F&V) polyphenols have numerous positive health effects, ascribed either to their antioxidant activity within the gastrointestinal tract (GIT) or to bioactivity of their absorbed metabolites. The effect of the F&V matrix on the gastrointestinal bioaccessibility of polyphenols was investigated along with its possible interaction with protein digestion. Minipigs were fed a complete meal with either cubed F&V (apple, plum, artichoke) added, or the corresponding phenolic extract (PE). Gastric and ileal chymes were kinetically collected over the postprandial period. The overall polyphenol bioaccessibility in the stomach was found to be 1.5% and 3.1% after F&V and PE consumption, respectively. The lower release rate from artichoke than from apple showed evidence of a plant effect. Flavanol monomers and glucoside conjugates were not recovered in the ileum in agreement with their absorption in the upper GIT. Interestingly, PE, but not F&V, significantly decreased the speed and efficiency of dietary protein digestion.