Basement-membrane thickening of the vocal cords in sudden infant death syndrome

Sudden infant death syndrome remains the leading cause of death in infants between the ages of 1 month and 1 year. Diagnosis at autopsy is usually reached by process of elimination, as no obvious cause of death is recognized. The larynges of 23 sudden infant death syndrome victims, as well as 6 infa...

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Bibliographic Details
Published inThe Laryngoscope Vol. 101; no. 5; p. 484
Main Authors Shatz, A, Hiss, J, Arensburg, B
Format Journal Article
LanguageEnglish
Published United States 01.05.1991
Subjects
Basement Membrane - pathology
Epithelium - pathology
Fetus
Humans
Infant
Larynx - pathology
Sudden Infant Death - pathology
Vocal Cords - pathology
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Summary:Sudden infant death syndrome remains the leading cause of death in infants between the ages of 1 month and 1 year. Diagnosis at autopsy is usually reached by process of elimination, as no obvious cause of death is recognized. The larynges of 23 sudden infant death syndrome victims, as well as 6 infants and 3 fetuses who died of other known causes, were examined in this study. While thickening of the basement membrane of the vocal cords was apparent in all sudden infant death syndrome victims, no such finding was present in the larynges of infants and fetuses dying of other causes. Thus, it is suggested that basement-membrane thickening may serve as a diagnostic tool for identification of sudden infant death syndrome at autopsy.
ISSN:0023-852X
DOI:10.1288/00005537-199105000-00007