Role and Efficacy of L-PRFmatrix in the Regeneration of Periodontal Defect: A New Perspective

The ultimate goal of periodontal therapy is to achieve complete wound healing and regeneration of the periodontal unit. The therapeutic use of L-PRF matrix constitutes a relatively new biotechnology that has been a breakthrough in the acceleration of hard and soft tissue healing. Platelet-rich fibri...

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Bibliographic Details
Published inJournal of clinical and diagnostic research Vol. 8; no. 12; pp. ZD03 - ZD05
Main Authors P, Anuroopa, Patil, Padmavathi, Kumar R, Vinaya, Kripal, Krishna
Format Journal Article
LanguageEnglish
Published India JCDR Research and Publications (P) Limited 01.12.2014
JCDR Research and Publications Private Limited
Subjects
blood products
Dentistry Section
l-prf matrix
periodontal defects
prp
regeneration
L-PRF matrix
Regeneration
Blood products
Periodontal defects
PRP
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Summary:The ultimate goal of periodontal therapy is to achieve complete wound healing and regeneration of the periodontal unit. The therapeutic use of L-PRF matrix constitutes a relatively new biotechnology that has been a breakthrough in the acceleration of hard and soft tissue healing. Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates, with simplified processing and without biochemical blood handling. The slow polymerization during PRF preparation seems to generate a fibrin network very similar to the natural one. Such a network leads to a more efficient cell migration and proliferation and thus cicatrization. This article proposes an overview of use of platelet-rich fibrin in management of periodontal hard and soft tissue defects and goes on to describe the clinical benefits of PRF and its advantage over PRP.
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2014/9240.5245