Myopic Macular Retinoschisis in Teenagers: Clinical Characteristics and Spectral Domain Optical Coherence Tomography Findings

• Published in: Scientific reports Vol. 6; no. 1; p. 27952
• Main Authors: Sun, Chuan-bin, You, Yong-sheng, Liu, Zhe, Zheng, Lin-yan, Chen, Pei-qing, Yao, Ke, Xue, An-quan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.06.2016; Nature Publishing Group
• Subjects: 692/499; 692/699/3161/3175; 692/700/1421; Adolescent; Adult; Atrophy; Female; Humanities and Social Sciences; Humans; Macula Lutea - diagnostic imaging; Macula Lutea - pathology; Macular Degeneration - complications; Macular Degeneration - diagnostic imaging; Macular Degeneration - pathology; Male; Morphology; multidisciplinary; Myopia; Myopia, Degenerative - diagnostic imaging; Myopia, Degenerative - pathology; Retinoschisis - complications; Retinoschisis - diagnostic imaging; Retinoschisis - pathology; Science; Teenagers; Tomography; Tomography, Optical Coherence; Ultrasonic imaging; Visual acuity; Young Adult
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/srep27952

To investigate the morphological characteristics of myopic macular retinoschisis (MRS) in teenagers with high myopia, six male (9 eyes) and 3 female (4 eyes) teenagers with typical MRS identified from chart review were evaluated. All cases underwent complete ophthalmic examinations including best corrected visual acuity (BCVA), indirect ophthalmoscopy, colour fundus photography, B-type ultrasonography, axial length measurement and spectral-domain optical coherence tomography (SD-OCT). The average age was 17.8 ± 1.5 years, average refractive error was −17.04 ± 3.04D, average BCVA was 0.43 ± 0.61 and average axial length was 30.42 ± 1.71 mm. Myopic macular degenerative changes (MDC) by colour fundus photographs revealed Ohno-Matsui Category 1 in 4 eyes and Category 2 in 9 eyes. Posterior staphyloma was found in 9 eyes. SD-OCT showed outer MRS in all 13 eyes, internal limiting membrane detachment in 7 eyes, vascular microfolds in 2 eyes and inner MRS in 1 eye. No premacular structures such as macular epiretinal membrane or partially detached posterior hyaloids were found. Our results showed that MRS rarely occurred in highly myopic teenagers and was not accompanied by premacular structures, severe MDC, or even obvious posterior staphyloma. This finding indicates that posterior scleral expansion is probably the main cause of MRS.