The Pathogenic Fungus Cryptococcus neoformans Expresses Two Functional GDP-Mannose Transporters with Distinct Expression Patterns and Roles in Capsule Synthesis

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Published inEukaryotic Cell Vol. 6; no. 5; pp. 776 - 785
Main Authors Cottrell, Tricia R, Griffith, Cara L, Liu, Hong, Nenninger, Ashley A, Doering, Tamara L
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.05.2007
Subjects
Amino Acid Sequence
Antigens, Fungal - biosynthesis
Biological Transport
Carrier Proteins - chemistry
Carrier Proteins - metabolism
Cryptococcus neoformans
Cryptococcus neoformans - cytology
Cryptococcus neoformans - metabolism
Gene Expression Regulation, Fungal
Genetic Complementation Test
Mannose - metabolism
Molecular Sequence Data
Mutation - genetics
Saccharomyces cerevisiae
Substrate Specificity
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T.R.C. and C.L.G. contributed equally to this work.
Present address: Medical Scientist Training Program, Johns Hopkins Medical School, Baltimore, MD 21205.
Corresponding author. Mailing address: Department of Molecular Microbiology, Washington University School of Medicine, Campus Box 8230, 600 South Euclid Avenue, St. Louis, MO 63110. Phone: (314) 747-5597. Fax: (314) 362-1232. E-mail: doering@wustl.edu
ISSN:1535-9778
1535-9786
DOI:10.1128/EC.00015-07