Phase angle and mortality: a systematic review

• Published in: European journal of clinical nutrition Vol. 73; no. 4; pp. 495 - 508
• Main Authors: Garlini, Luíza M., Alves, Fernanda D., Ceretta, Luciane B., Perry, Ingrid S., Souza, Gabriela C., Clausell, Nadine O.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.04.2019; Nature Publishing Group
• Subjects: 692/699; 692/700/2814; Bioelectricity; Clinical Nutrition; Epidemiology; Internal Medicine; Literature reviews; Medical prognosis; Medicine; Medicine & Public Health; Metabolic Diseases; Mortality; Phase shift; Public Health; Review Article; Systematic review
• ISSN: 0954-3007; 1476-5640; 1476-5640
• DOI: 10.1038/s41430-018-0159-1

Background/objectives The phase angle, expressed through bioelectrical impedance, has been studied as a prognostic marker in several health conditions. As this issue is still conflicting, the question whether this parameter correlates with mortality in the most diverse clinical situations remains. Therefore, this study aimed to evaluate the relationship between phase angle and mortality through a systematic review of the literature. Subjects/methods This research was conducted in electronic databases (Pubmed, Embase, Cochrane, Lilacs, Scielo, e Scopus), and included studies that had phase angle as a variable of interest and mortality/survival as an outcome. Data were extracted independently by two reviewers and disagreements were assessed by a third reviewer. Results Forty-eight of 455 papers were assessed and an amount of 42 showed a correlation between phase angle and mortality. Conclusions Phase angle seems to be a good indicator for mortality in many clinical situations and can be used in screening individuals prone to this outcome.