Limited Model Antigen Expression by Transgenic Fungi Induces Disparate Fates during Differentiation of Adoptively Transferred T Cell Receptor Transgenic CD4+ T Cells: Robust Activation and Proliferation with Weak Effector Function during Recall

• Published in: Infection and Immunity Vol. 80; no. 2; pp. 787 - 797
• Main Authors: Wüthrich, Marcel, Ersland, Karen, Pick-Jacobs, John C, Gern, Benjamin H, Frye, Christopher A, Sullivan, Thomas D, Brennan, Meghan B, Filutowicz, Hanna I, O'Brien, Kevin, Korthauer, Keegan D, Schultz-Cherry, Stacey, Klein, Bruce S
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.02.2012
• Subjects: Animals; Antigens, Fungal - genetics; Antigens, Fungal - metabolism; Biological and medical sciences; Blastomyces - genetics; Blastomyces - immunology; CD4-Positive T-Lymphocytes - physiology; Cell Differentiation; Cell Movement; Fundamental and applied biological sciences. Psychology; Fungal Proteins - genetics; Fungal Proteins - metabolism; Gene Expression Regulation, Fungal; Lung - cytology; Lung Diseases, Fungal - immunology; Lung Diseases, Fungal - microbiology; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Immunity and Vaccines; Microbiology; Miscellaneous; Mycology; Receptors, Antigen, T-Cell - genetics; Thy-1 Antigens - genetics; Thy-1 Antigens - metabolism; Antigen; Fungi; Cell proliferation; CD4 T lymphocyte; T cell receptor; Models; Immunity
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.05326-11

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