Electroporation of Synthetic DNA Antigens Offers Protection in Nonhuman Primates Challenged with Highly Pathogenic Avian Influenza Virus

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Published inJournal of Virology Vol. 83; no. 9; pp. 4624 - 4630
Main Authors LADDY, Dominick J, JIAN YAN, DRAGHIA-AKLI, Ruxandra, WEINER, David B, KHAN, Amir S, ANDERSEN, Hanne, COHN, Amanda, GREENHOUSE, Jack, LEWIS, Mark, MANISCHEWITZ, Jody, KING, Lisa R, GOLDING, Hana
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.05.2009
American Society for Microbiology (ASM)
Subjects
Animals
Biological and medical sciences
Electroporation
Fundamental and applied biological sciences. Psychology
Genetic Vectors - genetics
Influenza A Virus, H5N1 Subtype - immunology
Influenza A Virus, H5N1 Subtype - pathogenicity
Influenza Vaccines - genetics
Influenza Vaccines - immunology
Macaca mulatta - immunology
Macaca mulatta - virology
Microbiology
Miscellaneous
Orthomyxoviridae Infections - immunology
Orthomyxoviridae Infections - pathology
Orthomyxoviridae Infections - prevention & control
Orthomyxoviridae Infections - transmission
Plasmids - genetics
Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains
Vaccines and Antiviral Agents
Vaccines, DNA - genetics
Vaccines, DNA - immunology
Virology
Virus Replication
Monkey
Orthomyxoviridae
Electroporation
Virology
Virus
Antigen
Pathogenicity
Vertebrata
Influenzavirus A
Mammalia
Avian influenzavirus
Animal
Primates
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Corresponding author. Mailing address: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104. Phone: (215) 349-8591. Fax: (215) 573-9436. E-mail: dbweiner@mail.med.upenn.edu
ISSN:0022-538X
1098-5514
DOI:10.1128/JVI.02335-08