CEUS LI-RADS: algorithm, implementation, and key differences from CT/MRI

Contrast-enhanced ultrasound (CEUS) is a specialized form of ultrasound (US) performed with an intravenous injection of microbubble contrast agents. It has been successfully used for a variety of applications including characterization of liver tumors. In April 2014, the American College of Radiolog...

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Bibliographic Details
Published inAbdominal imaging Vol. 43; no. 1; pp. 127 - 142
Main Authors Wilson, Stephanie R., Lyshchik, Andrej, Piscaglia, Fabio, Cosgrove, David, Jang, Hyun-Jung, Sirlin, Claude, Dietrich, Christoph F., Kim, Tae Kyoung, Willmann, Juergen K., Kono, Yuko
Format Journal Article
LanguageEnglish
Published New York Springer US 01.01.2018
Springer Nature B.V
Subjects
Algorithms
Computed tomography
Contrast agents
Diagnostic systems
Gastroenterology
Hepatology
Imaging
Intravenous administration
Liver
Liver cancer
Magnetic resonance imaging
Medical diagnosis
Medicine
Medicine & Public Health
Radiology
Tumors
Ultrasonic imaging
Ultrasound
HCC
Diagnosis
LI-RADS
CEUS
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Summary:Contrast-enhanced ultrasound (CEUS) is a specialized form of ultrasound (US) performed with an intravenous injection of microbubble contrast agents. It has been successfully used for a variety of applications including characterization of liver tumors. In April 2014, the American College of Radiology (ACR) convened a working group of international experts to develop ACR CEUS Liver Imaging Reporting and Data System (CEUS LI-RADS). An initial version of CEUS LI-RADS was published in August 2016. Although the CEUS LI-RADS concept and principles for liver lesion characterization, using dynamic contrast enhancement features, are similar to those for CT or MRI, there are significant differences between CT/MRI and CEUS LI-RADS. Therefore, CEUS LI-RADS has different diagnostic features and a unique characterization algorithm. The size of a lesion, the type and degree of arterial phase enhancement, the presence of washout, and the timing and degree of washout are the major features used for categorization. This paper describes key differences between CT/MRI and CEUS, and provides a diagnostic algorithm of CEUS LI-RADS with detailed, step-by-step instructions and imaging examples of CEUS LI-RADS categories.
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ISSN:2366-004X
2366-0058
2366-0058
DOI:10.1007/s00261-017-1250-0