Photo-transformation of pharmaceutically active compounds in the aqueous environment: a review
In the past few years, the fate and transportation of pharmaceutically active compounds (PhACs) in aqueous environments have raised significant concerns among the public, scientists and regulatory groups. Photodegradation is an important removal process in surface waters. This review summarizes the...
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| Published in | Environmental science--processes & impacts Vol. 16; no. 4; pp. 697 - 72 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.01.2014
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| Subjects | |
| Online Access | Get full text |
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| Summary: | In the past few years, the fate and transportation of pharmaceutically active compounds (PhACs) in aqueous environments have raised significant concerns among the public, scientists and regulatory groups. Photodegradation is an important removal process in surface waters. This review summarizes the last 10 years (2003-2013) of studies on the solar or solar-simulated photodegradation of PhACs in aqueous environments. The PhACs covered include: beta-blockers, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), histamine H
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-receptor antagonists, lipid regulators, carbamazepine, steroid hormones, and X-ray contrast media compounds. Kinetic studies, degradation mechanisms and toxicity removal are the three major topics involved in this review. The quantum yield for the direct photolysis of PhACs and the bimolecular reaction rate constants of PhACs with reactive oxygen species (ROS), such as the &z.rad;OH radical and singlet oxygen, are also summarized. This information is not only important to predict the PhAC photodegradation fate, but also is very useful for advanced treatment technologies, such as ozone or advanced oxidation processes.
This review summarizes the last 10 years (2003-2013) of studies on the solar or solar-simulated photodegradation of pharmaceutically active compounds (PhACs) in aqueous environments. |
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| Bibliography: | Dr Weihua Song is currently a Professor at the Department of Environmental Science and Engineering at Fudan University. He received a B.S. in Environmental Chemistry and M.S. in Environmental Engineering from Nanjing University in 1999 and 2002. He completed his Ph.D. with Professor Kevin E. O'Shea at Florida International University in 2006. He was a postdoctoral fellow, working with Prof. William J. Cooper, at University of California, Irvine. His research interests are in the area of Environmental Chemistry. Particularly, he focuses on the photochemical fate of emerging contaminates in aqueous environments. Other topics are advanced oxidation processes for the removal of these contaminates from drinking water, wastewater and water for reuse purposes. Shuwen Yan is currently a Ph.D. student at the Department of Environmental Science and Engineering at Fudan University. She received her B.S. in Environmental Science from Qingdao University and M.S. in Environmental Engineering from the Chinese Research Academy of Environmental Sciences. Then she pursued her Ph.D. degree under the supervision of Professor Weihua Song. Her current research interests are in the area of the photo-transformation of pharmaceuticals in surface water. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 2050-7887 2050-7895 |
| DOI: | 10.1039/c3em00502j |